Miguel Ángel Lago Ángel
PhD, Postdoctoral researcher

RESEARCH INTERESTS

During my PhD I developed a methodology for the in-vivo characterization of the biomechanical behavior of the breast using medical images. This estimation was performed using an iterative search algorithm which optimizes the elastic constants of the constitutive models of the breast tissues. The search is based on the iterative variation of these parameters in order to increase the similarity between a simulated deformation of the organ and the real one. The methodology is based on the simulation of the compression of the breast during an MRI-guided biopsy. This research allowed me to stay at the University of Pennsylvania in one of the best research groups dedicated to simulate the breast anatomy, the X-ray Physics Laboratory.

I moved to University of California, Santa Barbara after finishing my PhD to work on image quality assessment. At UCSB I have been developing models of the human visual system. We study how humans explore 3D volumes such as Magnetic Resonance Images (MRI) or Digital Breast Tomosynthesis (DBT) by using an eye tracker. We developed a new foveated visual model observer that processes the image differently depending on the distance to the fixation point. Thus, things that are far from the fixation point would be processed with less accuracy. This model was incorporated to an eye movement model and a 3D scroll model (for 3D images) and proved to predict human performance when reading volumetric images, unlike traditional standard model observers. This new human model observer can be used to get an estimation of the image quality and, ultimately, can be used to improve it.

EDUCATION

2014

PhD. in Computer Engineering
Universitat Politècnica de València, Valencia, Spain

  • Thesis topic: A new approach for the in-vivo characterization of the biomechanical behavior of the breast and the cornea
  • Advisors: Prof. Dr. Carlos Monserrat Aranda and Dr. María José Rupérez Moreno
  • Qualification: Excellent Cum Laude
  • Download

2011

Master Degree in Artificial Intelligence, Pattern Recognition and Digital Imaging
Universitat Politècnica de València, Valencia, Spain

  • Thesis topic: Volume Comparison: application to the analysis of the behavior of biomechanical models of organs
  • Advisor: Prof. Dr. Carlos Monserrat Aranda

2009

Computer Engineer
Universitat Politècnica de València, Valencia, Spain

  • Best student record award

EXPERIENCE

2016 - now

Postdoctoral Researcer at Vision and Image Understanding LabUniversity of California, Santa Barbara, California, USA

  • Development of foveated visual model observers to assess imagequality in 3D Digital Breast Tomosynthesis.
  • Supervision of Prof. Miguel P. Eckstein and Dr. Craig K. Abbey

2015 - 2016

Research Engineer at Universitat Politècnica de València

2012 - 2013

Visiting scholar at University of Pennsylvania, Philadelphia, USA

  • Department of Radiology: X-ray Physics Lab
  • Supervision of Dr. Andrew D. Maidment and Dr. Predrag R. Bakic

2009 - 2014

PhD Student at Universitat Politècnica de València

  • Thesis Topic: A new approach for the in-vivo characterization of thebiomechanical behavior of the breast and the cornea

2009

Internship at SETIVAL

  • Software developer for mobile devices and interactive television

2009

Internship at Tissat

PUBLICATIONS

2019

Lago, M. A., Abbey, C. K., Eckstein, M. P., A foveated channelized Hotelling search model predicts dissociations in human performance in 2D and 3D images. doi.org/10.1117/12.2511777. In Proc.SPIE, Medical Imaging, 2019.

2018

Lago, M. A., Abbey, C. K., Barufaldi, B., Bakic, P. R., Weinstein, S. P., Maidment A. D.,Eckstein, M. P., Interactions of lesion detectability and size across single-slice DBT and 3D DBT. doi.org/10.1117/12.2293873. In Proc. SPIE, Medical Imaging, 2018.

Abbey, C. K.,Lago, M. A., Eckstein, M. P., Observer templates in 2D and 3D localization tasks. doi.org/10.1117/12.2293026. In Proc. SPIE, Medical Imaging, 2018.

Eckstein, M. P.,Lago, M. A., Abbey, C. K., Evaluation of search strategies formicrocalcifications and masses in 3D images. doi.org/10.1117/12.2293871. In Proc. SPIE, Medical Imaging, 2018.

Barufaldi, B., Bakic, P. R., Pokrajac, D. D.,Lago, M. A., Maidment A. D., Developingpopulations of software breast phantoms for virtual clinical trials. doi.org/10.1117/12.2318473. In Proc. of International Workshop on Breast Imaging (IWBI 2018), 2018.

2017

Rupérez M. J., Martínez-Martínez F., Martínez-Sober M.,Lago, M. A., Lorente D., Bakic P. R., Serrano-López A. J., Martínez-Sanchis S., Monserrat C., Martín-Guerrero J. D., Modeling the Mechanical Behavior of the Breast Tissues Under Compression in Real Time. doi.org/10.1007/978-3-319-68195-5_63. In VipIMAGE 2017. ECCOMAS 2017

M.A. Lago, M.P. Eckstein, C.K. Abbey. Foveated model observers to predict human performance in 3D images. doi:10.1016/10.1117/12.2252952. Proc. SPIE 10136, Medical Imaging 2017

Miguel P. Eckstein ; Miguel A. Lago ; Craig K. Abbey. The role of extra-foveal processing in 3D imaging. doi:10.1117/12.2255879. Proc. SPIE 10136, Medical Imaging 2017

2016

D. Lorente, F. Martínez-Martínez, M.J. Rupérez, M.A. Lago, M. Martínez-Sober, P. Escandell-Montero, J.M. Martínez-Martínez, S. Martínez-Sanchis, A.J. Serrano-López, C. Monserrat, J.D. Martín-Guerrero (2016). A framework for modelling the biomechanical behaviour of the human liver during breathing in real time using machine learning. doi:10.1016/j.eswa.2016.11.037. Expert Systems with Applications

2015

Lago, M. A., Rupérez, M. J., Monserrat, C., Martínez-Martínez, F, Martínez-Sanchis, S., Larra, E., Díez-Ajenjo, M. A. and Peris-Martínez, C. (2015). Patient-specific simulation of the intrastromal ring segment implantation in corneas with keratoconus. doi:10.1016/j.jmbbm.2015.07.023. Journal of the Mechanical Behavior of Biomedical Materials

Lago, M. A., Rupérez, M., Martínez-Martínez, F., Martínez-Sanchis, S., Bakic, P. R. and Monserrat, C. (2015). Methodology based on genetic heuristics for in-vivo characterizing the patient-specific biomechanical behavior of the breast tissues. doi:10.1016/j.eswa.2015.05.058. Expert Systems with Applications

Lago, M. A., Rupérez, M. J., Martínez-Martínez, F., Monserrat, C., Larra, E., Güell, J. L. and Peris-Martínez, C. (2015). A new methodology to in-vivo estimate the elastic constants that characterize the patient-specific biomechanical behavior of the human cornea. doi:10.1016/j.jbiomech.2014.11.009. Journal of Biomechanics

2014

Lago, M. A. , Rupérez, M., Martínez-Martínez, F. and Monserrat, C. (2014). Genetic algorithms for estimating the biomechanical behavior of breast tissues. doi:10.1109/BHI.2014.6864475. In Proceedings of IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), pages 760-763

2013

Martínez-Martínez, F., Lago, M. A., Rupérez, M. J. and Monserrat, C. (2013). Analysis of several biomechanical models for the simulation of lamb liver behaviour using similarity coefficients from Medical Image. doi:10.1080/10255842.2011.637492. Computer Methods in Biomechanics and Biomedical Engineering

Martínez-Martínez, F., Rupérez, M.J., Martín-Guerrero, J.D., Monserrat, C., Lago, M.A., Pareja, E., Brugger, S. and López-Andújar, R. Estimation of the elastic parameters of human liver biomechanical models by means of medical images and evolutionary computation. doi:10.1016/j.cmpb.2013.05.005. Computer Methods and Programs in Biomedicine

HONORS

2014

Student Oral Communication Award, IEEE-EMBS International Conference on Biomedical and Health Informatics, Valencia, Spain

2013

Student Poster Award at the 11th International Symposium on Computer Methods in Biomechanichs and Biomedical Engineering, Salt Lake City, UT

2012

TEE Erasmus Mundus Scholarship

2010

Doctoral Scholarship of Spanish Ministry of Education

2009

Best Student Record Award of the Promotion

2006

Second category award in Data Structures and Algorithms course

OTHER SKILLS

Programming Languages: Matlab, Python, PHP, C, C++, Java, JavaScript

Others: HTML, SQL, CSS, LATEX

Coursera: Machine Learning, Data Science

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